Beatrice (Valeria Bruni Tedeschi) is talkative manipulative, which stylize the millionaire rotating in an environment of higher spheres. Donatella (Micaela Ramazzotti, privately wife Virzìego) is a sensitive introverted of tattooed and fragile body, which hides a dark secret of his past. In the comedy Paola Virzìego these two patients' therapeutic center for women with mental health problems "connect friendship. One afternoon I decide to escape and seek happiness and love in the free world "healthy" people.

It's a cross between "Thelma and Louise" and "Flight Over the Cuckoo's Nest" made a sensation at this year's Cannes Film Festival, where the film was shown in the section of the Quinzaine des Réalisateurs. The film also won the award one of the most important Italian film awards Nastro d'Argento (Silver Ribbon), awarded by critics and journalists, in five categories. Valeria Bruni Tedeschi for his role has been nominated for the European Film Awards.